The Clinically Proven Benefits of Eggshell Calcium
In studies, eggshell calcium (found in Membrell’s BONEhealth) has been shown to be up to 20% more absorbable than other forms of calcium carbonate1 and as absorbable as or better than most other forms of calcium3, 4 commonly found in supplements. Research reveals that eggshell calcium’s superior bioavailability is derived from naturally occurring transporter proteins inherent in the eggshell matrix.2 This natural source of calcium that is easily 
utilized by the body has been shown in multiple human clinical studies to not only stop bone loss but to also build bone mineral density (BMD).4-8 Eggshell calcium produces increased BMD in healthy women within 12 months7 (See graph) and in osteoporotic women in as little as 4 months.6 Another clinical study in both osteoporotic men and women showed that eggshell calcium reduced pain and bone resorption and increased mobility and BMD after 6 months.8 Eggshell calcium has even been shown in vitro to stimulate chondrocyte differentiation and cartilage growth.9
The mineral profile of eggshell calcium represents a unique combination of essential nutrients for bone health. It not only provides a highly concentrated source of calcium, but also provides relevant levels of other trace minerals necessary for bone health including strontium, magnesium, zinc, and copper. Research has shown that strontium enhances bone mineralization through a dual-action of stimulating bone formation by osteoblasts and inhibiting bone resorption (destruction) by osteoclasts.10
1. Schaafsma A and Beelen GM: Eggshell powder, a comparable or better source of calcium than purified calcium carbonate: piglet studies. J Sci Food Agric 1999, 79:1596-1600.
2. Daengprok W, Garnjanagoonchorn W, Naivikul O, Pornsinlpatip P, Issigonis K and Mine Y: Chicken eggshell matrix proteins enhance calcium transport in the human intestinal epithelial cells, Caco-2. J Agric Food Chem 2003, 51(20):6056-6061. 3. Tsugawa N, Okano T, Higashino R, et al: Bioavailability of Calcium from Calcium Carbonate, DL-Calcium Lactate, L-Calcium Lactate, and Powdered Oyster Shell Calcium in Vitamin D-Deficient or -Replete Rats. Biol Pharm Bull 1995, 18(5):677-682. 4. Deroisy R, Zartarian M, Meurmans L, et al: Acute Changes in Serum Calcium and Parathyroid Hormone Circulating Levels Induced by the Oral Intake of Five Currently Available Calcium Salts in Healthy Male Volunteers. Clin Rheum 1997, 16(3):249-253. 5. Rovensky J, Stancikova M, Masaryk P, Svik K and Istok R: Eggshell calcium in the prevention and treatment of osteoporosis. Int J Clin Pharmacol Res 2003, 23:83-92. 6. Schaafsma A and Pakan I: Short-term effects of a chicken egg shell powder enriched dairy-based products on bone mineral density in persons with osteoporosis or osteopenia. Bratisl Lek Listy 1999, 100:651-656. 7. Schaafsma A, van Doormaal JJ, Muskiet FA, Hofstede GJ, Pakan I and van der Veer E: Positive effects of a chicken eggshell powder-enriched vitamin-mineral supplement on femoral neck bone mineral density in healthy late post-menopausal Dutch women. Br J Nutr 2002, 87:267-275. 8. Makai E and Chudacek J: The treatment of osteoporosis with Biomin H. Arch Gerontol Geriatr 1991, 2:487-490. 9. Pavlikova D, Rovensky J, Marek J, Schreiberova O, and Rovenska E: The effect of Biomin H on in vitro chicken embryonic cartilage growth (in Slovak). Rheumatologia 1995, 9(4):185-192. 10. Marie P: Strontium ranelate: a dual mode of action rebalancing bone turnover in favour of bone formation. Curr Opin Rheumatol 2006, 18:S11-15. 11. Mutlu M, Argun M, Kilic E, Saraymen R, Yazar S: Magnesium, zinc and copper status in osteoporotic, osteopenic and normal post-menopausal women. J Int Med Res 2007, 35(5):692-695. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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